Nefazadone-induced acute dystonic reaction

Authors
Burda, A Webster, K Leikin, JB Chan, SB Stokes, KA
Citation
A. Burda et al., Nefazadone-induced acute dystonic reaction, VET HUM TOX, 41(5), 1999, pp. 321-322
Citations number
12
Categorie Soggetti
Veterinary Medicine/Animal Health
Journal title
VETERINARY AND HUMAN TOXICOLOGY
ISSN journal
01456296 → ACNP
Volume
41
Issue
5
Year of publication
1999
Pages
321 - 322
Database
ISI
SICI code
0145-6296(199910)41:5<321:NADR>2.0.ZU;2-9
Abstract
A 53-y-o patient presented approximately 2 h after taking her first dose of nefazadone. Chief complaint was lip smacking with hand and arm gesturing. The patient also took 25 mg meclizine which she had used before with no adv erse effects. Diphenhydramine followed by benztropine led to resolution of symptoms within 1 h. Patient subsequently used meclizine with no untoward r eactions. Nefazadone should be added to the list of agents that cause acute dystonic reactions.