O. Cabaleiro et al., Valveless interface for two-dimensional reversed-phase microchromatography(mu-RPLC)-capillary zone electrophoresis (CZE), ANALUSIS, 27(5), 1999, pp. 468-471
Single stage separation systems have limitations in resolving multicomponen
t mixtures and two-dimensional systems have higher peak capacities. A valve
less interface for hyphenating Reversed-phase Microchromatography (mu-RPLC)
and Capillary Zone Electrophoresis (CZE) -highly orthogonal separation met
hods- is presented. which main innovation is a third electrode. Design and
operation of the interface as well as some preliminary results obtained by
combining FIA and mu-RPLC with CZE are shown.