Patterns of macrolide resistance determinants among community-acquired Streptococcus pneumoniae isolates over a 5-year period of decreased macrolide susceptibility rates

Authors
Oster, P Zanchi, A Cresti, S Lattanzi, M Montagnani, F Cellesi, C Rossolini, GM
Citation
P. Oster et al., Patterns of macrolide resistance determinants among community-acquired Streptococcus pneumoniae isolates over a 5-year period of decreased macrolide susceptibility rates, ANTIM AG CH, 43(10), 1999, pp. 2510-2512
Citations number
22
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
43
Issue
10
Year of publication
1999
Pages
2510 - 2512
Database
ISI
SICI code
0066-4804(199910)43:10<2510:POMRDA>2.0.ZU;2-A
Abstract
Erythromycin resistance rates were found to be increased, from 7.1 in 1993 to 32.8% in 1997, among community-acquired Streptococcus pneumoniae isolate s from the Siena area of central Italy. Most of the erythromycin-resistant isolates carried ermAM determinants and were also resistant to josamycin an d clindamycin, whereas a minority (5.8%) carried mefA determinants and rema ined susceptible to the latter drugs.