Prevalence of antimicrobial resistance in respiratory tract isolates of Streptococcus pneumoniae: Results of a Canadian national surveillance study

Authors
Zhanel, GG Karlowsky, JA Palatnick, L Vercaigne, L Low, DE Hoban, DJ
Citation
Gg. Zhanel et al., Prevalence of antimicrobial resistance in respiratory tract isolates of Streptococcus pneumoniae: Results of a Canadian national surveillance study, ANTIM AG CH, 43(10), 1999, pp. 2504-2509
Citations number
11
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
43
Issue
10
Year of publication
1999
Pages
2504 - 2509
Database
ISI
SICI code
0066-4804(199910)43:10<2504:POARIR>2.0.ZU;2-2
Abstract
From October 1997 to November 1998, 1,180 respiratory tract isolates of Str eptococcus pneumoniae were collected from 18 medical centers in 9 of the 10 Canadian provinces. Penicillin-intermediate and -resistant isolates occurr ed at rates of 14.8 and 6.4% respectively, and these rates varied considera bly by geographic region. Trimethoprim-sulfamethosazole, tetracycline, and macrolide rates of nonsusceptibility were 12.2, 10.6, and 8.0 to 9.3%, resp ectively. The most potent agents studied were newer fluoroquinolones.