In vitro susceptibilities of Mycoplasma hominis to six fluoroquinolones asdetermined by E test

Twenty isolates of Mycoplasma hominis were tested for their susceptibility to six fluoroquinolones by the E test. The MICs at which 90% of the isolate s were inhibited (in micrograms per milliliter) were as follows: sparfloxac in, 0.031; clinafloxacin, moxifloxacin, and trovafloxacin, 0.063; levofloxa cin, 0.25; and ciprofloxacin, 0.5. Increasing the amount of inoculum or inc ubation in CO2 elevated MICs by less than or similar to 1 dilution. E tests produce fluoroquinolone MICs comparable to those obtained by agar and micr obroth dilution for M. hominis.