A retrospective study of bursa of Fabricius from 90 necropsied ostriches fr
om Florida farms was performed. Eighty-five bursas showed lymphoid necrosis
and/or depletion, and acute to chronic inflammation. Rounded cytoplasmic i
nclusions were noted within bursal macrophages of 17 birds. Ultrastructural
ly, these inclusions comprised arrays of icosahedral virions with a diamete
r of 60 to 65 nm, suggesting possibly reovirus or birnavirus, Further work
is needed to classify and determine the pathogenic significance of this vir
us in the ostrich.