Studies on enzymatic hydrolysis of thymidin-3 '-yl thymidin-5 '-yl phosphorofluoridates and the corresponding phosphorothiofluoridates

Authors
Misiura, K Bollmark, M Stawinski, J Stec, WJ
Citation
K. Misiura et al., Studies on enzymatic hydrolysis of thymidin-3 '-yl thymidin-5 '-yl phosphorofluoridates and the corresponding phosphorothiofluoridates, CHEM COMMUN, (20), 1999, pp. 2115-2116
Citations number
24
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
20
Year of publication
1999
Pages
2115 - 2116
Database
ISI
SICI code
1359-7345(1999):20<2115:SOEHOT>2.0.ZU;2-U
Abstract
Spleen or snake venom nuclease-assisted cleavage of P-F bonds in nucleotide s bearing a phosphorofluoridate moiety occurs at negatively charged phospha tes only.