Auditory brainstem responses, electrocochleograms, and cochlear microphonics in the myelin deficient mutant hamster 'bt'

Citation
R. Naito et al., Auditory brainstem responses, electrocochleograms, and cochlear microphonics in the myelin deficient mutant hamster 'bt', HEARING RES, 136(1-2), 1999, pp. 44-48
Citations number
9
Categorie Soggetti
da verificare
Journal title
HEARING RESEARCH
ISSN journal
03785955 → ACNP
Volume
136
Issue
1-2
Year of publication
1999
Pages
44 - 48
Database
ISI
SICI code
0378-5955(199910)136:1-2<44:ABREAC>2.0.ZU;2-2
Abstract
Electrophysiological studies of the auditory pathway were performed on the mutant hamster 'bt' which is known to have myelin deficiencies in the centr al nervous system. Auditory brainstem responses (ABRs), electrocochleograms (EcochGs), and cochlear microphonics (CMs) were recorded. ABRs in 'bt' dem onstrated markedly transformed waveforms with significantly prolonged laten cies. EcochG in 'bt' showed significantly prolonged NI latencies of the com pound action potentials (CAPs) while 'bt' showed normal CMs. The myelin def icient mutant hamster 'bt' may have myelin deficiencies not only in the bra instem auditory pathway but also in the cochlear nerve. (C) 1999 Elsevier S cience B.V. All rights reserved.