Ed. Herzog et al., CIRCADIAN-RHYTHMS IN MOUSE SUPRACHIASMATIC NUCLEUS EXPLANTS ON MULTIMICROELECTRODE PLATES, Brain research, 757(2), 1997, pp. 285-290
The suprachiasmatic nucleus (SCN) of the mammalian hypothalamus functi
ons as a circadian pacemaker. This study used multimicroelectrode plat
es to measure extracellular action potential activity simultaneously f
rom multiple sites within the cultured mouse SCN. Neurons within the i
solated mouse SCN expressed a circadian rhythm in spontaneous firing r
ate for weeks in culture.