Objective: Evaluation of the association between air pollution and mortalit
y and morbidity is becoming ever more complex owing to changes in inner-cit
y air pollution, marked by decreasing values for all main pollutants save t
hose associated with traffic. This has led to the need for the study of new
epidemiological scenarios in which most pollutants are below guideline val
ues. Nonetheless, the health effects are significant. Methods: This report
presents the results of a statistically based model for real-time forecasti
ng of mortality and morbidity in Madrid, with meteorological and pollution
series serving as inputs. Results and conclusions: Not only did the models
perform well with correlation coefficients between predicted and observed v
alues (r = 0.683 for mortality, I = 0.681 for morbidity), but they enabled
quantification of the impact of air pollution on mortality and morbidity (w
ith increases ranging from 1.8% to 12% for mortality and from 2.3% to 18% f
or morbidity for a 25-mu g/m(3) increase in pollutants). Moreover, attentio
n should be drawn to the observation that the model proved to be easy to im
plement and operate on a routine basis.