Macroglossia and speech in Beckwith-Wiedemann syndrome: a sample survey study

In a sample survey study (questionnaires filled out by parents), all 40 pat ients with Beckwith-Wiedemann Syndrome (BWS) presented with macroglossia. A rticulation problems were reported in 29 of them, which persisted in some f ollowing corrective tongue surgery. The impression emerges that the value o f surgical treatment needs prospective assessment, that the parents are ins ufficiently informed, and that the adequacy of direct articulation therapy in BWS needs to be evaluated.