This article presents the main findings of the study of the Global Burden o
f Disease (GBD). The GBD assessed global health needs in 1990, and projecte
d trends to the year 2020. Its approach to measuring health status differs
from earlier ones because it takes into account not only the burden due to
premature death but also that caused by non-fatal health outcomes. The GBD
is expressed in a single indicator-the DALY (Disability Adjusted Life Year)
-which sums the number of years lost due to premature death and the number
of years lived with a disability. Findings from the GBD offered significant
surprises, which challenge the traditional emphasis of public health polic
y on infectious diseases. First, the study showed that the epidemiological
transition was already well advanced in developing regions. Second, it show
ed that the burden due to mental illness, such as depression, alcohol depen
dence, and schizophrenia has been vastly underestimated by the traditional
approach, which takes into account deaths but not disability. Third, it hig
hlighted the important burden due to injuries, particularly among young adu
lt males worldwide.