We describe a case of pyoderma gangrenosum VV which presented with severe w
ound breakdown after elective hip replacement. The patient was treated succ
essfully with minimal wound debridement and steroids. This diagnosis should
always be considered when confronted with an enlarging painful skin lesion
which does not grow organisms when cultured and fails to respond to antibi
otic therapy, especially if there are similar lesions in other sites. In pa
tients who have a past history of pyoderma gangrenosum, prophylactic steroi
ds may be indicated at the time of surgery or may be required early in the
postoperative period.