BRAIN-GUT INDUCTION OF HEAT-SHOCK-PROTEIN (HSP)-70 MESSENGER-RNA BY PSYCHOPHYSIOLOGICAL STRESS IN RATS

Authors
FUKUDO S ABE K HONGO M UTSUMI A ITOYAMA Y
Citation
S. Fukudo et al., BRAIN-GUT INDUCTION OF HEAT-SHOCK-PROTEIN (HSP)-70 MESSENGER-RNA BY PSYCHOPHYSIOLOGICAL STRESS IN RATS, Brain research, 757(1), 1997, pp. 146-148
Citations number
12
Categorie Soggetti
Neurosciences
Journal title
Brain research → ACNP
ISSN journal
00068993
Volume
757
Issue
1
Year of publication
1997
Pages
146 - 148
Database
ISI
SICI code
0006-8993(1997)757:1<146:BIOH(M>2.0.ZU;2-4
Abstract
Restraint water-immersion stress-induced expression of heat shock prot ein (HSP)70 mRNA in the cerebral cortex and stomach of rats was evalua ted bg Northern blotting. Cerebral and gastric HSP70 mRNA significantl y increased in the 6 h-stressed rats and the amount of mRNA measured a s optical densities was highest in the 12 h-stressed rats. These data confirmed our previous observations and suggest that families of HSPs play a salient cytoprotective role in stress-vulnerable organs.