Severe hypoglycaemia caused by raised insulin-like growth factor II in disseminated breast cancer

Authors
Bessell, EM Selby, C Ellis, IO
Citation
Em. Bessell et al., Severe hypoglycaemia caused by raised insulin-like growth factor II in disseminated breast cancer, J CLIN PATH, 52(10), 1999, pp. 780-781
Citations number
10
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research Diagnosis & Treatment
Journal title
JOURNAL OF CLINICAL PATHOLOGY
ISSN journal
00219746 → ACNP
Volume
52
Issue
10
Year of publication
1999
Pages
780 - 781
Database
ISI
SICI code
0021-9746(199910)52:10<780:SHCBRI>2.0.ZU;2-1
Abstract
A 60 year old woman with disseminated ductal carcinoma of the breast develo ped non-islet cell. tumour induced hypoglycaemia (NICTH). The concentration s of the two insulin-like growth factors, IGF-I anal IC;F-EI, were < 2 nmol /l and 94.1 nmol/l, respectively. The IGF-II to IGF-I ratio was > 47 (norma l < 10). Insulin (< 3 mu/l) and C peptide (< 100 pmol/l) were both undetect able.