Quaternization and dequaternization of pyrazoles in solvent-free conditions: Conventional heating versus microwave irradiation

Authors
Diez-Barra, E de la Hoz, A Sanchez-Migallon, A Elguero, J
Citation
E. Diez-barra et al., Quaternization and dequaternization of pyrazoles in solvent-free conditions: Conventional heating versus microwave irradiation, J HETERO CH, 36(4), 1999, pp. 889-894
Citations number
25
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
JOURNAL OF HETEROCYCLIC CHEMISTRY
ISSN journal
0022152X → ACNP
Volume
36
Issue
4
Year of publication
1999
Pages
889 - 894
Database
ISI
SICI code
0022-152X(199907/08)36:4<889:QADOPI>2.0.ZU;2-S
Abstract
We report a study on the quaternization and dequaternization of pyrazoles b y conventional heating and microwave irradiation in solvent-free conditions . Microwave irradiation produces an acceleration in the quaternization rate and a rapid equilibration between quaternized and non quaternized products . Dequaternization is also more rapid and a change on the selectivity is ob served using symmetric pyrazolium salts.