Direct functionalization of 4,5-dichloropyridazin-6-one

Authors
Chung, HA Kweon, DH Kang, YJ Park, JW Yoon, YJ
Citation
Ha. Chung et al., Direct functionalization of 4,5-dichloropyridazin-6-one, J HETERO CH, 36(4), 1999, pp. 905-910
Citations number
6
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
JOURNAL OF HETEROCYCLIC CHEMISTRY
ISSN journal
0022152X → ACNP
Volume
36
Issue
4
Year of publication
1999
Pages
905 - 910
Database
ISI
SICI code
0022-152X(199907/08)36:4<905:DFO4>2.0.ZU;2-X
Abstract
Direct functionalization of 4,5-dichloropyridazin-6-one with some nucleophi les in seven solvents gave regioselectively 5-halo-4-substituted-pyridazin- 6-ones as main product. Reaction of 4,5-dichlorapyridazin-6-one with 2-merc aptopyrimidine (2 equivalents) also afforded 4,5-di(pyrimidin-2-ylsulfanyl) pyridazinone as the main product.