An outbreak of Salmonella serogroup Saphra (S. saphra) infections was studi
ed by laboratory-based surveillance, case-control and trace-back studies, a
nd a survey of cantaloupe preparation practices. Twenty-four patients with
S. saphra infections had illness onsets between 23 February and 15 May 1997
; 75% were less than or equal to 6 years old; 23% were hospitalized, Case p
atients were more likely than controls to have consumed cantaloupe (88% vs,
45%; matched odds ratio [MOR], 15.5; 95% confidence interval [CI], 1.7-139
) and precut cantaloupe (59% vs. 19%; MOR, 14.5; 95% CI, 1.6-128), The trac
e-back study identified 1 growing region in Mexico as the source of cantalo
upes for 95% of the patients who ate cantaloupes, Only 17% of case patients
washed cantaloupes before cutting them. This outbreak is another example o
f gastrointestinal disease in the United States associated with imported co
ntaminated produce. Consumers and retailers should wash cantaloupes before
cutting them; there should be international efforts to ensure food safety.