Association of CCR5 del 32 with reduced risk of asthma

Citation
Ip. Hall et al., Association of CCR5 del 32 with reduced risk of asthma, LANCET, 354(9186), 1999, pp. 1264-1265
Citations number
5
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Journal title
LANCET
ISSN journal
01406736 → ACNP
Volume
354
Issue
9186
Year of publication
1999
Pages
1264 - 1265
Database
ISI
SICI code
0140-6736(19991009)354:9186<1264:AOCD3W>2.0.ZU;2-W
Abstract
We report that Individuals carrying the CCR5 Delta 32 mutation, a naturally occurring variant of the C-C chemokine receptor 5 (CCR5), are at reduced r isk of developing asthma, These data suggest a possible explanation for the high prevalence of this mutation in the general population.