Doppler flowmetry in the differentiation of biological characteristics of ovarian cancer

Citation
V. Lehotska et al., Doppler flowmetry in the differentiation of biological characteristics of ovarian cancer, NEOPLASMA, 46(4), 1999, pp. 249-252
Citations number
13
Categorie Soggetti
Onconogenesis & Cancer Research
Journal title
NEOPLASMA
ISSN journal
00282685 → ACNP
Volume
46
Issue
4
Year of publication
1999
Pages
249 - 252
Database
ISI
SICI code
0028-2685(1999)46:4<249:DFITDO>2.0.ZU;2-B
Abstract
On basis of ultrasonographic structural criteria and Doppler flowmetry in a group of 76 patients with ovarian cancer, benign lesions were discovered i n 59 patients and malignant lesions in 17 patients (77.6% and 22.4%, respec tively). Surgical intervention was indicated according to the clinical find ings and following of the trend of organ-specific oncomarkers in 32 out of 76 patients (42.1%). The stratification involved 17 patients with sonomorph ologically/Doppler-flowmetry - diagnosed malignancy as well as 15 patients with sonographically diagnosed benign ovarian tumor. The clinical findings were histologically verified in all 32 patients. Histology confirmed malign ant tumor in 16 patients, 1 histologically borderline malignancy and 15 ben ign tumors. The Doppler-flowmetry showed 94.1% sensitivity, 93.3% specifici ty, 93.3% positive predictive value, and 93.75% accuracy.