Fever during the early postoperative period traditionally has not been cons
idered an indication of a postoperative wound infection or breakdown. Atele
ctasis is considered the most likely source for these early fevers. We stud
ied 200 consecutive patients who underwent major head and neck surgery that
involved reconstruction with a pharyngeal suture line. Patients were divid
ed into 2 groups: those who had preoperative irradiation and those who did
not. All patients had prophylactic antibiotic coverage, and all patients ha
d identical suture material for closure. We showed a high correlation betwe
en fever (>101.5 degrees F) that developed in the first 48 hours and eventu
al fistula formation and wound infection. We also studied length of hospita
lization and number of days until decannulation and resumption of oral feed
ings. Our data indicate that in those patients in whom fistulas developed,
early detection led to earlier healing and rehabilitation.