Pentavalent antimonial drugs used for the treatment of leishmaniasis have b
een associated with sudden deaths, probably due to the development of ventr
icular tachyarrhythmias. Prolongation of the QT interval and ventricular ta
chyarrhymias have been described in patients on amiodarone therapy. We repo
rt a case of recurrent torsades de pointes following treatment with pentava
lent antimonial drugs and amiodarone. (C) 1999 Elsevier Science Ireland Ltd
. All rights reserved.