Synthesis of [1,2-b] and [2,1-b]quinazoline ring systems via suitably substituted alpha-cyanoamines

Authors
Le Gall, E Malassene, R Toupet, L Hurvois, JP Moinet, C
Citation
E. Le Gall et al., Synthesis of [1,2-b] and [2,1-b]quinazoline ring systems via suitably substituted alpha-cyanoamines, SYNLETT, (9), 1999, pp. 1383-1386
Citations number
23
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
9
Year of publication
1999
Pages
1383 - 1386
Database
ISI
SICI code
0936-5214(199909):9<1383:SO[A[R>2.0.ZU;2-K
Abstract
A novel entry into tetrahydro-6H-isoquino[1,2-b] quinazoline and hexahydro- 5aH-pyrido[2, 1-b]quinazoline ring systems is outlined employing 1,2,3,4-te trahydroisoquinoline and piperidine as starting material. The anodic cyanat ion of N-substituted aliphatic amines constitute the key step of the synthe sis of the quinazolines 3 and 9.