Unexpected formation of O-methoxycarbonyl cyanohydrin showing potential asa protective group of ketones

Authors
Poirier, D Berthiaume, D Boivin, RP
Citation
D. Poirier et al., Unexpected formation of O-methoxycarbonyl cyanohydrin showing potential asa protective group of ketones, SYNLETT, (9), 1999, pp. 1423-1425
Citations number
13
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
9
Year of publication
1999
Pages
1423 - 1425
Database
ISI
SICI code
0936-5214(199909):9<1423:UFOOCS>2.0.ZU;2-I
Abstract
A one-step procedure using methyl cyanoformate and a secondary alkylamine w as reported to efficiently transform ketones into O-methoxycarbonyl cyanohy drins. This functional group shows interesting potential in protecting grou p chemistry.