Enantioselective syntheses of key A-ring precursors of 1 alpha, 25-dihydroxyvitamin D-3 and analogues

Authors
Anne, S Yong, W Vandewalle, M
Citation
S. Anne et al., Enantioselective syntheses of key A-ring precursors of 1 alpha, 25-dihydroxyvitamin D-3 and analogues, SYNLETT, (9), 1999, pp. 1435-1437
Citations number
38
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
9
Year of publication
1999
Pages
1435 - 1437
Database
ISI
SICI code
0936-5214(199909):9<1435:ESOKAP>2.0.ZU;2-D
Abstract
A practical synthesis of (3S, 5R) oct-1-en-7-yne-3,5-diol derivatives 7 inv olving a catalytic enantioselective aldol reaction is described. Also a new synthesis of (3S, 5R) non-1-en-7-yne-3,5,9-triol derivatives 3, starting f rom (2S, 4S)-1,2:4,5-diepoxy-pentane 2 is reported.