A regio and stereospecific synthesis of carbacephem antibiotics

Citation
G. Ruano et al., A regio and stereospecific synthesis of carbacephem antibiotics, SYNLETT, (9), 1999, pp. 1441-1443
Citations number
20
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
9
Year of publication
1999
Pages
1441 - 1443
Database
ISI
SICI code
0936-5214(199909):9<1441:ARASSO>2.0.ZU;2-X
Abstract
In this article we report a short and practical route to chiral carbacephem s 1 based on an asymmetric Staudinger reaction for building the beta-lactam ring, and on a tandem elimination-conjugate addition for making the second ring.