New synthesis of differently fused pyridazinoquinolines

Citation
V. Dal Piaz et al., New synthesis of differently fused pyridazinoquinolines, SYNLETT, (9), 1999, pp. 1453-1455
Citations number
23
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
9
Year of publication
1999
Pages
1453 - 1455
Database
ISI
SICI code
0936-5214(199909):9<1453:NSODFP>2.0.ZU;2-G
Abstract
Treatment of properly 6-(substituted aryl)-5-acetyl-4-chloro- and 4-methylt hio-3(2H)-pyridazinones with SnCl2/HCl afforded pyridazino[4,3-c] quinolino nes 9 and 10, whereas the pyridazino[4,5-b] quinolinone derivative 6 was pr epared by reduction of the 5-acetyl-4-anilino-6-phenyl-3(2H)-pyridazinone w ith sodium borohydride, followed by dehydration with polyphosphoric acid (P PA).