A concise total synthesis of (+/-)-A80915G, a member of the napyradiomycinfamily of antibiotics

Authors
Takemura, S Hirayama, A Tokunaga, J Kawamura, F Inagaki, K Hashimoto, K Nakata, M
Citation
S. Takemura et al., A concise total synthesis of (+/-)-A80915G, a member of the napyradiomycinfamily of antibiotics, TETRAHEDR L, 40(42), 1999, pp. 7501-7505
Citations number
29
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
42
Year of publication
1999
Pages
7501 - 7505
Database
ISI
SICI code
0040-4039(19991015)40:42<7501:ACTSO(>2.0.ZU;2-F
Abstract
(+/-)-A80915G, a member of the napyradiomycin family of antibiotics, has be en synthesized from 1-amino-2,5-dimethoxy-4-nitrobenzene via the sequential palladium-catalyzed cross-coupling reactions (the Stille reaction) of aryl halides with allyltins and the Diels-Alder reaction of the chloroquinone w ith the Danishefsky-Brassard diene. (C) 1999 Elsevier Science Ltd. All righ ts reserved.