Citation
F. Iwasaki et al., Catalytic activation of trichlorosilane for efficient and stereoselective reduction of ketones, TETRAHEDR L, 40(42), 1999, pp. 7507-7511
Citations number
14
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039
→ ACNP
Volume
40
Issue
42
Year of publication
1999
Pages
7507 - 7511
Database
ISI
SICI code
0040-4039(19991015)40:42<7507:CAOTFE>2.0.ZU;2-G
Abstract
Some kinds of N-formyl cyclic amine derivatives were found to be effective
activators for trichlorosilane to reduce ketones. Namely, a catalytic amoun
t of these activators were sufficient to complete the reduction of ketones
with trichlorosilane, and the reduction of ketones by trichlorosilane with
optically active activators gave enantiomerically enriched sec-alcohols in
some extent of optical yields (up to 51% ee). (C) 1999 Elsevier Science Ltd
. All rights reserved.