Asymmetric synthesis of densely functionalized 3-substituted 3-hydroxy-beta-lactams via novel, highly stereoselective Baylis-Hillman and allylation reactions of enantiopure 3-oxo-2-azetidinones

Authors
Alcaide, B Almendros, P Aragoncillo, C
Citation
B. Alcaide et al., Asymmetric synthesis of densely functionalized 3-substituted 3-hydroxy-beta-lactams via novel, highly stereoselective Baylis-Hillman and allylation reactions of enantiopure 3-oxo-2-azetidinones, TETRAHEDR L, 40(42), 1999, pp. 7537-7540
Citations number
39
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
42
Year of publication
1999
Pages
7537 - 7540
Database
ISI
SICI code
0040-4039(19991015)40:42<7537:ASODF3>2.0.ZU;2-#
Abstract
New asymmetric routes based on both Baylis-Hillman and allylation reactions of enantiopure 3-oxo-2-azetidinones are used for the highly stereoselectiv e, efficient preparation of densely functionalized 3-substituted 3-hydroxy- beta-lactams. (C) 1999 Published by Elsevier Science Ltd. All rights reserv ed.