Novel route to b-fused thiazoles starting from a 2-chloro-1-phenacylpyridinium salt and KSCN. Crystal structures of thiazolo- and oxazolo[3,2-a]pyridinium thiocyanates

Authors
Babaev, EV Bush, AA Orlova, IA Rybakov, VB Zhukov, SG
Citation
Ev. Babaev et al., Novel route to b-fused thiazoles starting from a 2-chloro-1-phenacylpyridinium salt and KSCN. Crystal structures of thiazolo- and oxazolo[3,2-a]pyridinium thiocyanates, TETRAHEDR L, 40(42), 1999, pp. 7553-7556
Citations number
19
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
42
Year of publication
1999
Pages
7553 - 7556
Database
ISI
SICI code
0040-4039(19991015)40:42<7553:NRTBTS>2.0.ZU;2-A
Abstract
Reaction of 2-chloro-1-phenacylpyridinium bromide 1a with KSCN led to 2-ami no-thiazolo[3,2-a]pyridinium salts 4a,b thus opening a novel route to fused thiazoles. In reaction with KSCN oxazolo[3,2-a]pyridinium perchlorate 2a w as converted to thiocyanate 2b. Crystal structures of thiocyanates 2b and 4 b were determined. (C) 1999 Elsevier Science Ltd. All rights reserved.