AN ANGULAR HYDROXYLATION ROUTE TO TAXANES - FACILE ACCESS TO THE BRIDGED AB RING-SYSTEM OF TAXOL

Authors
KERKAR B DOKHAC D FETIZON M GUIR F
Citation
B. Kerkar et al., AN ANGULAR HYDROXYLATION ROUTE TO TAXANES - FACILE ACCESS TO THE BRIDGED AB RING-SYSTEM OF TAXOL, Tetrahedron letters, 38(18), 1997, pp. 3223-3226
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
18
Year of publication
1997
Pages
3223 - 3226
Database
ISI
SICI code
0040-4039(1997)38:18<3223:AAHRTT>2.0.ZU;2-P
Abstract
The 5-mesyloxy-12-alcohol 11b, obtained in eight steps from 5a, via an gular hydroxylation is transformed by Grob fragmentation into the high ly functionalized taxane precursor 12. (C) 1997 Elsevier Science Ltd.