P. Lingstrom et al., EFFECTS OF FREQUENT MOUTHRINSES WITH PALATINOSE AND XYLITOL ON DENTALPLAQUE, European journal of oral sciences, 105(2), 1997, pp. 162-169
The aim was to evaluate the effects of frequent mouthrinses with palat
inose, xylitol and a mixture of palatinose and xylitol on plaque pH, p
laque formation and cariogenic microorganisms. 15 subjects refrained f
rom toothbrushing during 3 test periods and rinsed 15 x daily for 4 d
with 10 ml of: (1) 50% palatinose, (2) 37.5% palatinose + 12.5% xylito
l, or (3) 50% xylitol. A contrast period with no mouthrinses was also
carried out. The 4 periods were carried out in a randomized order with
a cross-over design. After the 4-day periods, 3 parameters were measu
red: (1) plaque pH during the first 30 min after a mouthrinse with pal
atinose, a mixture of palatinose and xylitol or xylitol alone, directl
y followed by a 2nd rinse with 10% sucrose; (2) number of mutans strep
tococci and lactobacilli in plaque and saliva; (3) plaque index. The m
ost pronounced pH drop for the sugar substitutes was found when rinsin
g with 50% palatinose after the palatinose period, and the least pH dr
op with 50% xylitol after the xylitol period. The sucrose rinse gave s
imilar pH fall after all 4 periods. The microbial data showed no diffe
rences between the 4 periods, but the mutans streptococcus counts in s
aliva decreased after the xylitol period in contrast to the 3 other pe
riods. Regarding the plaque index, xylitol gave lower scores compared
to the other 3 periods.