Effects of fluvastatin on prothrombotic and fibrinolytic factors in type 2diabetes mellitus

Authors
Tan, KCB Janus, ED Lam, KSL
Citation
Kcb. Tan et al., Effects of fluvastatin on prothrombotic and fibrinolytic factors in type 2diabetes mellitus, AM J CARD, 84(8), 1999, pp. 934
Citations number
20
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
AMERICAN JOURNAL OF CARDIOLOGY
ISSN journal
00029149 → ACNP
Volume
84
Issue
8
Year of publication
1999
Database
ISI
SICI code
0002-9149(19991015)84:8<934:EOFOPA>2.0.ZU;2-D
Abstract
The effects of fluvastatin therapy on parameters of coagulation and fibrino lysis were evaluated in patients with diabetic dyslipidemia in a randomized , placebo-controlled study. Fluvastatin therapy was associated with a small reduction in factor Vn coagulant activity, von Willebrand factor, and in p lasminogen activator inhibitor 1 and tissue plasminogen activator antigens, but the effects of fluvastatin on hemostatic factors were much less marked than its effects on plasma lipids.