O. David et S. Jakate, Multifocal granular cell tumor of the esophagus and proximal stomach with infiltrative pattern - A case report and review of the literature, ARCH PATH L, 123(10), 1999, pp. 967-973
Citations number
27
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research Diagnosis & Treatment
The granular cell tumor is a solitary painless nodule that arises most comm
only on the skin or the tongue. The vast majority are benign. Approximately
5% to 9% of granular cell tumors have been reported in the gastrointestina
l tract, most commonly in the esophagus. We report a case of a 45-year-old
African American woman with multifocal granular cell tumors of the esophagu
s and proximal stomach. Two lesions within the distal esophagus and proxima
l stomach were characteristic nodular granular cell tumors. Within the mid
esophagus there was poorly defined transmural involvement by benign-appeari
ng granular cells. This pattern of infiltration by benign cells is uncharac
teristic. A review of the literature with emphasis on the determination of
malignancy is also presented.