A study of the Chueta population has been carried out to establish the
genetic relationships between the Chuetas and other Jewish and non-Je
wish circum-Mediterranean populations and to identify which markers di
scriminate better between these populations. The analyses used were pr
incipal components analysis, factorial analysis of correspondences, an
d stepwise discriminant analysis, The results indicate that most of th
e Jewish communities resemble each other and other Middle Eastern popu
lations, because of their common origin, but they also have affinities
with their host peoples. The results also agree with those of most re
searchers in the importance of G6PD, FY, and MN as geographic markers
and in the role of HP, GLO1, and Rh as indicators the Middle Eastern o
rigin of the Jews but differ with respect to the geographic pattern of
ABO. Moreover, the Jewish origin of the Chuetas remains evident in th
eir genetic pool, although they resemble their neighboring populations
more than other Jewish populations. Finally, HP, G6PD, ABO and Rh are
the most important variables in determining the position of the Chuet
as with respect to other Jewish and non-Jewish populations.