A semi-structured model for the growth and beta-Galactosidase production by fed-batch fermentation of Kluyveromyces marxianus

Authors
Bojorge, N Valdman, B Acevedo, F Gentina, JC
Citation
N. Bojorge et al., A semi-structured model for the growth and beta-Galactosidase production by fed-batch fermentation of Kluyveromyces marxianus, BIOPROC ENG, 21(4), 1999, pp. 313-318
Citations number
34
Categorie Soggetti
Biotecnology & Applied Microbiology
Journal title
BIOPROCESS ENGINEERING
ISSN journal
0178515X → ACNP
Volume
21
Issue
4
Year of publication
1999
Pages
313 - 318
Database
ISI
SICI code
0178-515X(199910)21:4<313:ASMFTG>2.0.ZU;2-E
Abstract
A model is proposed to describe the growth and beta-Galactosidase productio n by Kluyveromyces marxianus. It shows good agreement with the experimental data over a range of conditions. It also reliably predicts the effect of g rowth rate on the productivity of the protein. The simplicity and accuracy of the model make it suitable for designing and implementing control and op timization strategies for the production of protein at large scale.