Disseminated histoplasmosis in immnunosuppressed patients rarely occurs in
nonendemic areas. Reported here is a case of disseminated histoplasmosis in
a patient who had undergone orthotopic liver transplantation and had never
traveled outside of France. The infection was most likely transmitted via
the liver allograft, since the organ donor had lived in an area highly ende
mic for the disease (French Guiana) 20 years earlier. Two years post-transp
lantation? none of the other patients who received allografts (heart, corne
a, kidneys) from the same donor had developed signs of infection.