Novel biocatalytic methodology: Low temperature enhanced enantioselectivity of enzyme catalyzed reactions in organic solvents

Authors
Ljubovic, E Majeric-Elenkov, M Avdagic, A Sunjic, V
Citation
E. Ljubovic et al., Novel biocatalytic methodology: Low temperature enhanced enantioselectivity of enzyme catalyzed reactions in organic solvents, FOOD TECH B, 37(3), 1999, pp. 215-224
Citations number
60
Categorie Soggetti
Biotecnology & Applied Microbiology
Journal title
FOOD TECHNOLOGY AND BIOTECHNOLOGY
ISSN journal
13309862 → ACNP
Volume
37
Issue
3
Year of publication
1999
Pages
215 - 224
Database
ISI
SICI code
1330-9862(199907/09)37:3<215:NBMLTE>2.0.ZU;2-I
Abstract
After recent reports in 1997/98, the low-temperature enhancement of enantio selectivity of the lipase-catalyzed acylations in organic solvents, emerges as a new lab-scale methodology in biocatalysis. The examples of effective production of enantiomerically pure compounds (EPC) at low temperatures, ei ther by kinetic resolution of racemates or by desymmetrization of prochiral substrates, are reviewed.