Borderline tumors of the ovary - An evolving concept

Background: Ovarian tumors of low malignant potential are proliferating int ermediate epithelial ovarian tumors capable of metastasis. Histologically t hey lie between adenomas and carcinomas. Despite their relatively high inci dence optimal management is often unclear. Methods: We reviewed 169 patients with ovarian tumors of LMP treated betwee n 1972 and 1995. Results: LMP is a histologic diagnosis. Some tumors of LMP show microinvasi on. Peritoneal implants can be invasive or noninvasive and this is of progn ostic relevance. So-called micropapillary carcinoma may be a specific subty pe of serous varian tumors of LMP. The goal of primary treatment is to accu rately stage the disease and remove it completely. Adjuvant treatment is ge nerally reserved for patients considered at high risk for recurrence. Conclusion: New genetic techniques may permit a more accurate classificatio n of ovarian tumors of LMP and more individualized treatment.