A cytotoxic acetophenone with a novel skeleton, isolated from Cynanchum taiwanianum

Citation
Pl. Huang et al., A cytotoxic acetophenone with a novel skeleton, isolated from Cynanchum taiwanianum, HELV CHIM A, 82(10), 1999, pp. 1716-1720
Citations number
8
Categorie Soggetti
Chemistry & Analysis",Chemistry
Journal title
HELVETICA CHIMICA ACTA
ISSN journal
0018019X → ACNP
Volume
82
Issue
10
Year of publication
1999
Pages
1716 - 1720
Database
ISI
SICI code
0018-019X(1999)82:10<1716:ACAWAN>2.0.ZU;2-6
Abstract
A novel acetophenone, cynantetrone (1), was isolated from the rhizome of Cy nanchum taiwanianum and its structure determined by spectroscopic methods. Compound 1 and cynandione B (3) showed significant in vitro cytotoxicity ag ainst T-24 cell lines, and 3 also against PLC/PRF/5 cell lines.