Claisen-Schmidt condensation in the solid state

Authors
Mogilaiah, K Rao, RB
Citation
K. Mogilaiah et Rb. Rao, Claisen-Schmidt condensation in the solid state, I J CHEM B, 38(7), 1999, pp. 869-871
Citations number
12
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY
ISSN journal
03764699 → ACNP
Volume
38
Issue
7
Year of publication
1999
Pages
869 - 871
Database
ISI
SICI code
0376-4699(199907)38:7<869:CCITSS>2.0.ZU;2-C
Abstract
An efficient and convenient procedure for the preparation of 3-cinnamoyl-2- methyl-1,8-naphthyridines 2 has been achieved by the Claisen-Schmidt conden sation of 3-acetyl-2-methyl-1,8-naphthyridine 1 with aromatic aldehydes in the presence of KOH in the solid state. The reaction proceeds efficiently a t room temperature in good yields and in a state of high purity.