Genotypic variability among 96 Trichophyton rubrum strains which displayed
different colony morphologies and were collected from four continents was i
nvestigated. Twelve markers representing 57 loci were analyzed by PCR finge
rprinting, amplified fragment length polymorphism, and random amplified mon
omorphic DNA markers. Interestingly, none of the methods used revealed any
DNA polymorphism, indicating a strictly clonal mode of reproduction and a s
trong adaptation to human skin.