Background. Symptoms consistent with bruxism are a common chief complaint i
n dental practice. The authors describe a case of bruxism likely induced by
the antidepressant venlafaxine and successfully treated with gabapentin.
Case Description. A case of bruxism, anxiety, insomnia and tremor is report
ed in a man with bipolar disorder that developed a few days after he initia
ted venlafaxine therapy for depression. The patient's psychiatrist prescrib
ed gabapentin for anxiety symptoms, and shortly thereafter the man experien
ced a complete resolution of the bruxism.
Clinical Implications. On the basis of this case and the available literatu
re, the authors conclude that bruxism secondary to antidepressant therapy m
ay be common. Thus, dentists should inquire about the use of these medicati
ons in patients who have bruxism. Gabapentin may offer promise in the treat
ment of this condition.