Involvement of the stomach by metastatic breast cancer

Background: Involvement of the stomach by metastatic breast cancer is uncom mon. There are no exact data about the frequency of gastric metastases duri ng life. Patients: In the last five years, 510 patients with breast cancer were seen at our hospital. Three patients were found with gastric metastases. These patients had a postmenopausal invasiv lobular breast cancer with advanced d isease including the peritoneum in two case. Two of three patients complain ed about epigastric symptoms. Results: Endoscopy showed linitis plastica and atypical ulcerations in two cases respectively. There was no indication to Helicobacter pylori Cytostat ic treatment and acid-blocking yielded to complete disappearance of the ulc ers. Conclusions: Metastatic involvement of the stomach should be considered red in patients with metastalic breast cancel; especially in patients with epi gastric symptoms invasive lobular carcinoma and malignant ascites. Endoscop ic features often are linitis plastica or malignant ulcer. Treatment of gas tric metastases corresponds to the palliative management of advanced breast cancer.