Non antibiotic-associated Colitis caused by Clostridium difficile in children: Two case reports

Infections with the grampositive bacterium Clostridium difficile occurs mos tly in worst ill, multimorbide patients treated with cytostatica or antibio tics. We report about two healthy children with pseudomembranous colitis ca used by Clostridium difficile without an underlying illness or a former his tory of antibiotic treatment. Result: In cases with a history of prolongated mucous diarrhoe one should c onsider an infection with Clostridium difficile. A pseudomembranous colitis with Clostridium difficile can be confirmed by the detection of the bacter ium, the toxin as well as the typically histological picture.