Neuro-ophthalmologic disorders affecting the afferent and efferent visual p
athways are frequently encountered by neurosurgeons in clinical practice. S
igns and symptoms of visual pathway dysfunction occur commonly as initial p
resenting features of neurosurgical diseases, including intracranial tumors
, aneurysms, arteriovenous malformations, carotid-cavernous fistulas, and c
arotid artery atherosclerotic disease. Visual loss and ocular motility diso
rders may also occur following surgery for such conditions. Prompt recognit
ion and localization of neuro-ophthalmologic signs and symptoms may be cruc
ial to effective diagnosis and management. This review concentrates on thos
e aspects of neuroanatomy that are most important to the diagnosis of affer
ent and efferent visual pathway lesions. The use of optic disc and fundus a
ppearance, visual fields, and ocular motility and pupillary findings is emp
hasized in the discussions on topographical diagnosis.