Transient rapid growth of uterine leiomyoma in a postmenopausal woman

We report a case of transient rapid growth of uterine leiomyoma in a postme nopausal woman. A 58-year old woman presented with a rapidly enlarging pelv ic tumor, from a 14-week to a 20-week gestational size in the one month. Tr anscervical needle biopsy revealed a smooth muscle tumor with 5 mitotic fig ures per 10 high power fields. However, surgical specimen obtained 1 month later revealed less than 1 mitotic figure per 100 high power fields. This v ariation may influence the final histopathological diagnosis because mitoti c index is believed to be one of the most reliable histopathological parame ters for differentiating between uterine leiomyoma and leiomyosarcoma.