Economic evaluation of the treatment of chronic wounds - Hydroactive wounddressings in combination with enzymatic ointment versus gauze dressings inpatients with pressure ulcer and venous leg ulcer in Germany

Objective: The treatment costs for pressure ulcers and venous leg ulcers we re estimated based on the hospital administrator's perspective in Germany. Design: A spreadsheet model using input data from various hospitals in Germ any was developed. Interventions: Five currently used treatment strategies were analysed: gauz e, impregnated gauze, calcium alginate and hydroactive wound dressing with enzymatic ointment. Participants: All cases used for and in the analysis were treated in the in patient setting (4 hospitals and 120 patients were included). Main outcome measures and results: The outcome distributions were calculate d using the Monte Carlo method. For the whole treatment process, the attrib utable costs for the hospital were calculated for different cases (severity ) and all treatment strategies (1997 values). The costs for treatment with gauze were the highest, whereas the costs for treatment with hydroactive wound dressings and enzymatic ointment were the lowest. The relation between personnel and material costs for gauze is appr oximately 95 to 5% and for hydroactive wound dressings 67 to 33%, respectiv ely. The cost savings per case were between 1196 deutschmark (DM) and DM982 6 using hydroactive wound dressings instead of gauze dressings (depending o n the severity of the pressure ulcer), and between DM135 and DM677 for veno us leg ulcers. The results were robust and did not change in any performed sensitivity analysis (parameter: 'personnel costs per minute', 'time requir ed for changing a wound dressing', 'total number of wound dressing changes' ). Conclusions: Despite the higher material costs of the hydroactive wound dre ssings in combination with enzymatic wound cleaning compared with other wou nd dressings, they should be recommended for the treatment of pressure ulce rs and venous leg ulcers. This therapy alternative brings about significant reductions in total costs for hospitals because of significant reductions in personnel costs and the duration of treatment.