M. Monaghan et al., A PILOT TRIAL TO EVALUATE THE GAMMA-INTERFERON ASSAY FOR THE DETECTION OF MYCOBACTERIUM-BOVIS INFECTED CATTLE UNDER IRISH CONDITIONS, Irish veterinary journal, 50(4), 1997, pp. 229
The gamma-interferon assay was evaluated in 203 M. bovis-infected catt
le which had previously been identified by the single intradermal comp
arative tuberculin test, and in 923 cattle from 13 herds which were co
nsidered free of tuberculosis. Eight methods were used to interpret th
e results and the proportion of infected cattle giving a positive resu
lt ranged from 56.2% to 87.7%. The proportion of cattle from herds con
sidered free of tuberculosis giving a positive result ranged from 3.4%
to 11.9%. These results suggest that the gamma-interferon assay is wo
rthy of further investigation for the diagnosis of tuberculosis in cat
tle in Ireland.